We have a very active program in
experimental HIV medicine, in particular immunotherapy and gene engineering an
HIV resistant immune system, and in gene-engineering monocytes/macrophages to
fight cancer. We use all kinds of in
vitro and in
vivo methods. Ultimate goal is to gain insight into HIV
pathogenesis, the immune network and to advance gene engineering as well as to provide
pre-clinical proof of concept for future clinical trials.
The laboratory of Dr. Speck is very well embedded in
the research place of Zurich and benefits from its unique scientific richness.
Notably, we have very active international collaborations for the gene
engineering part (Prof. Michael Pepper, University of Pretoria (SA) and Prof.
Karl-Heinz Krause, University of Geneva (CH)), for studying IFNs (Prof. Gideon
Schreiber, Weizmann Institute of Science, Israel) and for immunotherapy (Prof.
Giuseppe Pantaleo, University of Lausanne and Prof. Renata Stripecke, University
The laboratory is well financed by various foundations,
among others by the Swiss National Science, Swiss Vaccine Institute and the
VonTobel Foundation. http://www.researcherid.com/rid/O-2433-2016